Dysfunctional brain circuits in psychiatry: new targets for deep brain stimulation?

by A.F. ten Brink

Institution: Universiteit Utrecht
Year: 2014
Keywords: Deep brain stimulation, structural imaging, functional imaging, psychiatric disorders
Record ID: 1255933
Full text PDF: http://dspace.library.uu.nl:8080/handle/1874/290010


Understanding mechanism of action of deep brain stimulation (DBS) on a neural level contributes to new insights concerning brain circuits underlying neuropsychiatric disorders, which seem to overlap. Studying the neural effects of DBS on emotion, cognition and behavior allows for a shift from the current diagnostic classification of psychiatric disorders towards dysfunctional circuits. Effects of DBS throughout the brain for different targets for obsessive-compulsive disorder, major depressive disorder, Tourette syndrome and Anorexia Nervosa are described by reviewing structural and functional imaging studies.