Dysfunctional brain circuits in psychiatry: new targets for deep brain stimulation?
Institution: | Universiteit Utrecht |
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Department: | |
Year: | 2014 |
Keywords: | Deep brain stimulation, structural imaging, functional imaging, psychiatric disorders |
Record ID: | 1255933 |
Full text PDF: | http://dspace.library.uu.nl:8080/handle/1874/290010 |
Understanding mechanism of action of deep brain stimulation (DBS) on a neural level contributes to new insights concerning brain circuits underlying neuropsychiatric disorders, which seem to overlap. Studying the neural effects of DBS on emotion, cognition and behavior allows for a shift from the current diagnostic classification of psychiatric disorders towards dysfunctional circuits. Effects of DBS throughout the brain for different targets for obsessive-compulsive disorder, major depressive disorder, Tourette syndrome and Anorexia Nervosa are described by reviewing structural and functional imaging studies.