AbstractsComputer Science

Students' learning of molecular modeling. The case of computer-aided drug design against malaria disease

by C.M.W. van Enckevort




Institution: Universiteit Utrecht
Department:
Year: 2014
Keywords: Molecular modeling
Record ID: 1255955
Full text PDF: http://dspace.library.uu.nl:8080/handle/1874/298078


Abstract

Models are important tools used in the production, dissemination and acceptance of scientific knowledge (Dori & Barak, 2001, p. 62). The skills to learn with, about and to construct a model are important for understanding in science. Within science education, especially in chemistry education, molecular modeling (construction of a model) received a more extensive place in the curriculum. Despite the importance of this topic, little is known about teaching molecular modeling in chemistry or science education and also the amount of teaching materials is limited. In this study, a design based experiment was performed to get an insight in students’ learning of molecular modeling. Within the context of drug design for malaria disease, students had to complete a curriculum unit in which they had to model a molecular analog. 24 students worked in teams of three students during the intervention of the curriculum unit. It was investigated which insights and learning outcomes the design acquired for students in the process of molecular modeling. Also the affection of the students was measured. Data was collected by using a set of questionnaires, analyzing the recorded audiotapes and written answers and doing a group interview. The audiotapes and written answers were coded, scored and compared to a reference framework drafted in a hypothetical learning trajectory (HLT) to get an insight in the learning outcomes of the students. An inter-rater reliability check was included to ensure reliability. The questionnaires and the interviews were used to map the (improved) insights in molecular modeling and the affection of the students. The outcomes of this study are promising for the future. Students show great affection for the curriculum unit and a clear insight is gained about the improvements which have to be implemented to improve students’ learning about molecular modeling.