AbstractsBiology & Animal Science

Abstract

List of papers. Papers I and III are removed from the thesis due to copyright restrictions. Paper I Christian Berger, Ute Krengel, Espen Stang, Ernesto Moreno, and Inger Helene Madshus Nimotuzumab and cetuximab block ligand-independent EGF receptor signaling efficiently at different concentrations Journal of Immunotherapy, 2011 Sep;34(7):550-5. <a href="http://dx.doi.org/10.1097/CJI.0b013e31822a5ca6">doi:10.1097/CJI.0b013e31822a5ca6</a> Paper II Christian Berger, Inger Helene Madshus and Espen Stang Cetuximab in combination with anti-human IgG antibodies efficiently down-regulates the EGF receptor by macropinocytosis NOTICE: this is the author’s version of a work that was accepted for publication in Experimental Cell Research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in: Experimental Cell Research 2012 Dec;318(20):2578-91. <a href="http://dx.doi.org/10.1016/j.yexcr.2012.09.001">doi:10.1016/j.yexcr.2012.09.001</a> Paper III Juliana Bentes Hughes, Christian Berger, Marianne Skeie Rødland, Max Hasmann, Espen Stang, and Inger Helene Madshus Pertuzumab increases epidermal growth factor receptor down-regulation by counteracting epidermal growth factor receptor-ErbB2 heterodimerization Molecular Cancer Therapeutics, 2009 Jul;8(7):1885-92. <a href="http://dx.doi.org/10.1158/1535-7163.MCT-09-0291">doi:10.1158/1535-7163.MCT-09-0291</a> Paper IV Tram Thu Vuong, Christian Berger, Vibeke Bertelsen, Marianne Skeie Rødland, Espen Stang, Inger Helene Madshus Preubiquitinated chimeric ErbB2 is constitutively endocytosed and subsequently degraded in lysosomes NOTICE: this is the author’s version of a work that was accepted for publication in Experimental Cell Research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in: Experimental Cell Research 2013 Feb;319(3):32-45. <a href="http://dx.doi.org/10.1016/j.yexcr.2012.10.010">doi:10.1016/j.yexcr.2012.10.010</a>