The neuro-humeral aspects of ulcer formation.
Institution: | McGill University |
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Department: | Department of Physiology. |
Degree: | MS. |
Year: | 1948 |
Keywords: | Physiology. |
Record ID: | 1527134 |
Full text PDF: | http://digitool.library.mcgill.ca/thesisfile125299.pdf |
In spite of the early and brilliant observations of clinical pathologists, notably Rokitansky, who first called attention to the association of brain damage and pathological changes in the stomach, suggesting a neurogenic basis for ulcer formation, this concept was for many decades overshadowed by the views of Virchow and his followers who held that peptic ulcer was essentially a local disease. Although the neurogenic concept was later supported by both experimental and clinical studies, it was not until the publication of Gushing*s Balfour Lecture, relating peptic ulcer to disturbances in the interbrain, that the interest in this aspect of ulcer formation was revived.[...]