AbstractsMedical & Health Science

Synthesis of nitro acridine derivatives.

by Martin Friedrich




Institution: University of Louisville
Department:
Degree: MS
Year: 1926
Record ID: 1527769
Full text PDF: http://ir.library.louisville.edu/etd/460


Abstract

At the present time there is not much known about derivatives of acridine. However, there are derivatives of acridine which are important as dyes, drugs and antiseptics. Chrysaniline, rheonine, benzoflavine, are examples of leather dyes which are used extensively. The theory of Perkins and Robinson, says that the acridine ring system is probably present in strychnine and brucine, so a further study of the derivatives of acridine may shed light on the true structure of these alkaloids. Some derivatives of acridine such as rivanol and acriflavine have a specific physiological effect, others are used as silver salts in killing of bacteria or trypanosomes, also in the curing of sleeping sickness in humans.