AbstractsWomens Studies

Abstract

The objective ofthis study was to determine the incidence of unique gennline mutations in the BRCAI and retinoblastoma (Rb) tumor suppressor genes in Japanese women diagnosed with ovarian cancer by Single-Strand Confonnation Polymorphism (SSCP) analysis. This thesis has been prepared as two chapters that have been submitted as two manuscripts. The first manuscript was submitted with collaborators to Human Mutation and the second manuscript was submitted to Cancer.