AbstractsBiology & Animal Science

A radiobiological basis for bioeffect planning

by David Wigg

Institution: University of South Australia, [1999
Degree: PhD
Year: 0
Keywords: Radiation Physiological effect; Radiobiology Measurement; Radiotherapy Measurement
Record ID: 1073940
Full text PDF: http://itupl-ura1.ml.unisa.edu.au:80/R/?func=dbin-jump-full&object_id=unisa34064


The main purpose of this thesis is to encourage the development of bioeffect planning as an experimental tool by which means bioeffect plans may be compared with standard isodose plans. This thesis also addresses the fundamental problems of the derivation of useful biological models for clinical application and the description of tumour and normal tissue parameter values and their variability. Particular emphasis has been placed on comparing the predictive value of the models and parameters against clinical results of fractionated and continuous irradiation either alone or combined.