AbstractsBiology & Animal Science

The Enigma of Tubulin Detyrosination - Functional Evidence from Plants

by Natalie Schneider

Institution: Universität Karlsruhe
Year: 2015
Record ID: 1101912
Full text PDF: http://digbib.ubka.uni-karlsruhe.de/volltexte/documents/3427749


Detyrosination of alpha-tubulin seems to be conserved over all eukaryotes. However, its biological function in plants has remained obscure. In order to get insight into the physiological function of tubulin detyrosination, I was phenotyping an overexpressor rice mutant, which is shifting the cycle towards the tyrosinated form. In a second approach an in vitro system was established in order to analyze what happens to microtubule polymerization if these conditions are changed outside a cell.