Some aspects of the protein-binding of steroids and thyroxine in human blood.
Institution: | McGill University |
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Department: | Department of Investigative Medicine. |
Degree: | PhD |
Year: | 1964 |
Keywords: | Investigative Medicine. |
Record ID: | 1579391 |
Full text PDF: | http://digitool.library.mcgill.ca/thesisfile116589.pdf |
Missing pg. 134. In 1961, Dr. C.J. Pattee and Dr. R. Gillies observed a decreased response of plasma 17-hydroxycorticoid levels when estrogen was administered to subjects with Laennec's cirrhosis. They postulated that these lower blood levels were due to a relative lack of the protein which binds corticoids in the blood. The present investigations were initiated by the author in an attempt to establish the validity of this hypothesis. [...]