Exploring relationships between stress and olfaction as mediated by neuropeptide y
Institution: | University of Tennessee – Chattanooga |
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Department: | |
Year: | 2016 |
Keywords: | Smell – Psychological aspects; Sensory evaluation |
Posted: | 02/05/2017 |
Record ID: | 2125208 |
Full text PDF: | http://scholar.utc.edu/theses/473 |
The negative correlation between olfactory sensitivity and depression has been well documented, but the biological processes underpinning the relationship are not understood. This study explored a potential relationship between olfactory sensitivity, stress, and resilience to stress, specifically examining neuropeptide y (NPY) as a mediator. In phase I, 197 UTC students participated in a survey measuring stress and resilience among other factors. Of this sample, 25 students volunteered for phase II, in which they took an olfactory threshold test and gave blood. Serum levels of cortisol and NPY were analyzed from blood samples. Correlational analyses suggest a positive effect of stress (p=.013) and a negative effect of resilience (p=.003) on olfactory thresholds, while biological markers were inconclusive. Future studies should incorporate the diagnosis of stress disorders, as biological markers may not significantly fluctuate based on non-clinical levels of stress. Advisors/Committee Members: Ozbek, Irene N., Foerder, Preston, G., Santiago, Manuel F., College of Arts and Sciences.