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by Yang Yang
Institution: | University of Waterloo |
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Year: | 2017 |
Keywords: | fall risk classification; non-faller; single faller; recurrent faller; smart wearable; physical activity; sleep; heart rate; community-dwelling older adults; resident assessment instrument (RAI); home care (HC) |
Posted: | 02/01/2018 |
Record ID: | 2153186 |
Full text PDF: | http://hdl.handle.net/10012/11778 |
Background: Falls are a serious problem especially in the aging population. To accurately identify individuals at risk for falls and mitigate the devastating effects caused by falls has become prominent to geriatrics and public health agencies. Leveraging wearable technologies and clinical assessment information may improve fall risk classification.Objectives: The overall objectives of this thesis project are to: (1) investigate the similarities and differences in physical activity (PA), heart rate (HR) and night sleep (SP) in a sample of community-dwelling older adults with varying fall histories, using a smart wrist-worn device; and (2) examine the risk factors for falls in the target population, create fall risk classification models and evaluate classification performances based on: i) wearable data, ii) the Resident Assessment Instrument for Home Care (RAI-HC), and iii) the combination of wearable data and the RAI-HC system.Methods: Two parallel studies were conducted in this project. Study I was a community-based cross-sectional study, utilizing the RAI-HC system to examine the risk factors for falls in older people. In the primary analysis, the ordinal attribute of previous falls (0, 1, and 2) was used as the outcome variable to build the proportional odds models (POM) for ordinal logistic regression. In the secondary analysis, the binary attribute of falls (yes/no) was used to distinguish fallers and non-fallers. Study II, a prospective, observational study was conducted to investigate the similarities and differences among three independent faller groups (non-fallers, single fallers, and recurrent fallers) based on the number of previous falls in a sample of older adults living in community, with continuous measurements of PA, HR and SP using a smart wearable device. Descriptive statistics and simple statistical analyses were conducted to test the differences between groups. The wearable and RAI-HC assessment data were further analyzed and utilized to create fall risk classification models, with two supervised machine learning algorithms: logistic regression (LR) and decision tree (DT). The calculation of a set of performance metrics was performed to evaluate the classification performance of each final model.Results: Study I: Of 167,077 individuals aged 65 in the RAI-HC data set, 113,529 (68.0%) had no history of falls, 27,320 (16.4%) had one fall, and 26,226 (15.7%) experienced multiple ( 2) falls. Unsteady gait, Activities of Daily Living (ADL) decline, ADL self-performance on transfer dependency, short-term memory problem, primary modes of locomotion (indoors), stair climbing, bladder continence, and limit going outdoors due to fear of falling were significant predictors of fall risk in both human and computer feature selection models derived from the Minimum Data Set-Home Care (MDS-HC). The Method of Assigning Priority Levels (MAPLe) (1 vs. 5: odds ratio (OR) = 0.20; 95% confidence internal (CI), 0.18-0.22), Changes in Health, End-Stage Disease, Signs, and Symptoms (CHESS) (0 vs. 5: OR =
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