Abstracts Category : Other

An investigation into the utility of the ImPACT neurocognitive screening tool with patients diagnosed with multiple sclerosis

by Carl Wurz

Objective: The objective of this study was to investigate the utility of the Immediate Post Concussion Assessment and Cognitive Testing (ImPACT) assessment tool in the neurocognitive screening of patients with Multiple Sclerosis (MS). Participants and Method: Patients diagnosed with Multiple Sclerosis (n = 29) were compared with a healthy control group (n = 20) of equivalent age, years of education, quality of education and estimated premorbid IQ. Measures included five ImPACT composite scores, the ImPACT Design Memory Delayed Recall subtest, the Symbol Digit Modalities Test (SDMT) that has shown prior sensitivity to cognitive dysfunction in MS groups, and the SDMT Delayed Recall test. T-test analyses compared test performances of the MS patient group with the control group; correlational analyses investigated the construct similarities between the ImPACT and SDMT tests. Results: There was a consistent trend for the MS patient group to perform worse than controls on all the neurocognitive tests. Significant differences accompanied by medium to high effect sizes were in evidence for ImPACT Reaction Time, ImPACT Cognitive Efficiency Index, ImPACT Design Memory Delayed Recall, SDMT, and SDMT Delayed Recall test. Correlational analyses revealed construct comparability between the ImPACT tests calling upon processing speed and the SDMT, as well as the IMPACT and SDMT delayed recall tasks. Conclusions: The results support the utility of the ImPACT test as a screening instrument for the detection of cognitive dysfunction in patients with MS. Tests tapping general cognitive efficiency, processing speed, reaction time, and delayed recall rather than immediate recall reveal particular utility as neurocognitive screening aids for patients with MS.