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How to conduct meta-analysis: a basic tutorial

by A Basu

Institution:	University of Canterbury
Year:	2017
Keywords:	Epidemiology; Evidence based medicine; Health policy; Public health; Statistics; Field of Research::11 - Medical and Health Sciences::1117 - Public Health and Health Services::111706 - Epidemiology; Field of Research::01 - Mathematical Sciences::010
Posted:	02/01/2018
Record ID:	2198402
Full text PDF:	http://hdl.handle.net/10092/14582

Abstract

Meta analysis refers to a process of integration of the results of many studies to arrive at evidence syn- thesis. Meta analysis is similar to systematic review; however, in addition to narrative summary that is conducted in systematic review, in meta analysis, the analysts also numerically pool the results of the studies and arrive at a summary estimate. In this paper, we discuss the key steps of conducting a meta analysis. We will discuss the steps of a simple meta-analysis with a demonstration of the key steps based on a published paper on meta-analysis and systematic review of the effectiveness of salt restricted diet on blood pressure control. This paper is a basic introduction to the process of meta-analysis. In subsequent papers in this series, we will show how you can conduct meta-analysis of diagnostic and screening studies, network meta analyses, and those of diagnostic and screening studies.